…who joined our lab for his Bachelor thesis. In cooperation with the Laboratory of Biochemistry (Prof. Dr. Dolf Weijers), he will study transcriptional regulators on the single-molecule level.
…who joined our lab for his Master thesis. Mattia is a student at the University of Bologna and, supported by an Erasmus fellowship, he will spend six months in Wageningen to work on the combination of single-molecule detection and novel microfluidic devices.
…who successfully defended his PhD thesis titled “Structural and kinetic characterization of DNA polymerases I and III from Escherichia coli” at the Spanish College in Bologna.
Koen joined our group for his Bachelor thesis. He will study the dynamics of DNA hairpins using smFRET. Jochem Vink started his Master thesis in the group of Dr. Stan Brouns (Laboratory of Microbiology). Jochem will be a frequent user of our super-resolution microscope.
…who is a PhD student at the University of Bologna working on DNA polymerases. He received an Erasmus fellowship to spend three months in our lab. He will study his favourite DNA polymerases using single-molecule FRET assays.
Good news! Our proposal “Nanofluidic devices for high-throughput single-molecule fluorescence detection (Nanofluidic-SMFD)” has been granted by the European Commission (FP7-PEOPLE-2013-CIG, #630992). The proposed work aims at utilising nanofluidic devices to overcome current limitations in single-molecule-fluorescence detection. Specifically, we are hoping to monitor enzymatic reactions such as DNA polymerisation in real time without immobilising any of the involved molecules to a surface as it is currently necessary. For this project, we will continue our collaboration with Klaus Mathwig (www.kmathwig.com).
…who joins the group for his master thesis. In close cooperation with the Laboratory of Microbiology, he is going to set up super-resolution microscopy in live bacteria.
…who joins the group to pursue his PhD thesis. He is going to study DNA polymerases interacting with DNA by employing single-molecule FRET techniques. He graduated in Molecular Life Sciences here at Wageningen University.
…who join the group for their Bachelor thesis. In close cooperation with the Laboratory of Biochemistry, we are going to look into Arabidopsis lines that express transcriptional regulators (Stef van der Krieken, project with Prof. Dr. Dolf Weijers) and plasma membrane steroid receptors (Stefan Hutten, project with Prof. Dr. Sacco de Vries).
A big welcome to Shazia Farouq (PhD student in the van Amerongen group)! Shazia will take over some of Andy’s projects, who left the group to pursue new endeavours. Thanks to Andy’s work in the last three months, we are now able to detect single fluorescent molecules on our microscope. Hooray!
Picture: Doubly labelled DNA (dyes: Cy3B and ATTO647N) immobilised on a glass surface. The green detection channel is on the left, red detection channel (FRET channel) on the right.